F26D10.3 | SMap | S_parent | Sequence | SUPERLINK_CB_IV
|
| Chromosome | IV |
|
Identity (5)
|
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Gene_info
| Gene_class | hsp
|
| | Phenotype | [C.elegansII] NMK. Encodes protein related to generic hsp70. Quite strong expression normally, only weak heat shock induction. [Heschl and Baillie 1990; BC] |
| |
GO_term
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GO:0009408 (2)
|
| | | GO:0008340
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IMP (2)
|
| | | GO:0005524
| IEA
| Inferred_automatically |
| |
Structured_description
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Provisional_description
| hsp-1 encodes hsp70A, a member of the heat shock family of proteins; hsp70A is closely related to the Drosophila heat inducible hsp70s and the S. cerevisiae SSA hsp70 subfamily; the hsp-1 gene is normally expressed throughout development and upon heat-shock the hsp-1 mRNA is enhanced 2-6 fold; down-regulation of hsp-1 via RNA interference results in a small reduction in the life-span of an age-1 mutant indicating that hsp-1 may play some role in regulating longevity. |
Paper_evidence
| WBPaper00001048
|
| | | | | | WBPaper00001320
|
| | | | | | WBPaper00013354
|
| | | | | Curator_confirmed | WBPerson324
|
| | | | | Date_last_updated | 17 Jun 2004 00:00:00 |
| | | | hsp-1 encodes hsp70A, a member of the heat shock family of proteins; hsp70A is closely related to the Drosophila heat inducible hsp70s and the S. cerevisiae SSA hsp70 subfamily; the hsp-1 gene is normally expressed throughout development and upon heat-shock the hsp-1 mRNA is enhanced 2-6 fold; down-regualtion of hsp-1 via RNA interference results in a small reduction in the life-span of an age-1 mutant indicating that hsp-1 may play some role in regulating longevity. |
Paper_evidence
| WBPaper00001048
|
| | | | | | WBPaper00001320
|
| | | | | | WBPaper00013354
|
| | | | | Person_evidence | WBPerson324
|
| | |
Concise_description
| hsp-1 encodes hsp70A, a member of the heat shock family of proteins; hsp70A is closely related to the Drosophila heat inducible hsp70s and the S. cerevisiae SSA hsp70 subfamily; the hsp-1 gene is normally expressed throughout development and upon heat-shock the hsp-1 mRNA is enhanced 2-6 fold; down-regulation of hsp-1 via RNA interference results in a small reduction in the life-span of an age-1 mutant indicating that hsp-1 may play some role in regulating longevity. |
| | | | hsp-1 encodes hsp70A, a member of the heat shock family of proteins; hsp70A is closely related to the Drosophila heat inducible hsp70s and the S. cerevisiae SSA hsp70 subfamily; the hsp-1 gene is normally expressed throughout development and upon heat-shock the hsp-1 mRNA is enhanced 2-6 fold; down-regualtion of hsp-1 via RNA interference results in a small reduction in the life-span of an age-1 mutant indicating that hsp-1 may play some role in regulating longevity. |
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Molecular_info (5)
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Experimental_info
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RNAi_result
| Cenix:122-e2
|
| | | Simmer:F26D10.3
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| | | Simmer:T28F3.2
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WB_RNAi_result (7)
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Expr_pattern
| Expr563
|
| | | Expr5002
|
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Y2H_target (4)
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Reference (17)
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| Method | Gene
|