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Gene: F33H1.2   

F33H1.2SMapS_parentSequenceF33H1
ChromosomeII
Identity (5)
Gene_info Gene_classgpd
Phenotype[C.elegansII] NMK. Encodes glyceraldehyde-3-phosphate-dehydrogenase, minor isozyme (GAPDHase-1),ubiquitous, predominant expression in embryo; sequence closest to gpd-1. [Barrios et al. 1989; HH]
GO_term (6)
Structured_description Provisional_description gpd-4 encodes one of four C. elegans glyceraldehyde-3-phosphate dehydrogenases (GAPDHs); by homology, GPD-4 is predicted to reversibly catalyze the oxidation and phosphorylation of glyceraldehyde-3-phosphate to 1,3-diphosphoglycerate during glycolysis; GPD-4 is required for embryonic and larval development; in C. elegans, GPD-4 and GPD-1 constitute the minor GAPDH isoenzymes and are expressed primarily in embryos, in all cell types. Paper_evidence WBPaper00000730
WBPaper00001143
Person_evidenceWBPerson1843
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
GPD-4 and GPD-1 are nearly identical, exhibiting 99% identity at the amino acid level.
Concise_descriptiongpd-4 encodes one of four C. elegans glyceraldehyde-3-phosphate dehydrogenases (GAPDHs); by homology, GPD-4 is predicted to reversibly catalyze the oxidation and phosphorylation of glyceraldehyde-3-phosphate to 1,3-diphosphoglycerate during glycolysis; GPD-4 is required for embryonic and larval development; in C. elegans, GPD-4 and GPD-1 constitute the minor GAPDH isoenzymes and are expressed primarily in embryos, in all cell types.
Molecular_info (6)
Experimental_info RNAi_result (5)
WB_RNAi_result (14)
Expr_patternExpr778
Y2H_targetY2H006956
Reference WBPaper00001143
WBPaper00001209
WBPaper00001634
WBPaper00001723
WBPaper00014145
WBPaper00003290
WBPaper00000730
WBPaper00013855
WBPaper00002006
MethodGene