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Gene: F39H11.3   

F39H11.3EvidencePaper_evidenceWBPaper00004192
SMapS_parentSequenceF39H11
ChromosomeI
Identity (5)
Gene_info Gene_classcdk
Alleletm1238
GO_term GO:0004672 IEA Inferred_automatically
GO:0005524 IEA Inferred_automatically
GO:0006468 IEA Inferred_automatically
GO:0004674 IEA Inferred_automatically
Structured_description Provisional_description (6)
Concise_descriptioncdk-8 encodes a member of the cyclin-dependent serine/threonine protein kinase family orthologous to human CDK8 (OMIM:603184) which functions in transcriptional regulation with the positive regulatory factor cyclin C, is associated with the RNA polymerase II holoenzyme, and may regulate gene-specific activators; CDK-8 also contains a glutamine/asparagine-rich domain; loss of cdk-8 function via RNA-mediated interference (RNAi) results in sterility in the injected hermaphrodite, suggesting that in C. elegans, CDK-8 may play a role in germ-line development.
Molecular_info (6)
Experimental_info RNAi_result (5)
WB_RNAi_result (6)
Reference WBPaper00004192
WBPaper00006530
WBPaper00010129
WBPaper00025388
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene