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GO_term: GO:0000364   

GO:0000364DefinitionCatalysis of the second transesterification reaction of U2-type spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure. The catalytic site is thought to be formed by U6 and/or U2 snRNAs and/or associated proteins.
Term 2nd U2-type spliceosomal transesterification activity
second U2-type spliceosomal transesterification activity
TypeMolecular_function
ParentInstance_ofGO:0000386
Attributes_of Index Ancestor (21)
Descendent GO:0004770
GO:0016740
GO:0008665
GO:0000364