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Gene: H04J21.3   

H04J21.3SMapS_parentSequenceH04J21
ChromosomeIII
Identity (5)
Gene_info Gene_classgip
Allele (6)
Contained_in_operonCEOP3075
Structured_description Provisional_descriptiongip-1 encodes the C. elegans homolog of Saccharomyces cerevisiae Spc98p, a gamma-tubulin-binding protein that with Spc97p forms part of a gamma-tubulin ring complex that can nucleate microtubule formation in vitro and in vivo; in C. elegans, GIP-1 is essential for embryogenesis and required for formation of centrosomal asters during interphase and formation of the mitotic spindle, but not for formation of mitotic asters; GIP-1 colocalizes with TBG-1/gamma-tubulin to centrosomes during interphase and mitosis; GIP-1 and TBG-1 are required reciprocally for centrosomal localization. Paper_evidence WBPaper00005041
WBPaper00005320
Person_evidenceWBPerson1843
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Concise_descriptiongip-1 encodes the C. elegans homolog of Saccharomyces cerevisiae Spc98p, a gamma-tubulin-binding protein that with Spc97p forms part of a gamma-tubulin ring complex that can nucleate microtubule formation in vitro and in vivo; in C. elegans, GIP-1 is essential for embryogenesis and required for formation of centrosomal asters during interphase and formation of the mitotic spindle, but not for formation of mitotic asters; GIP-1 colocalizes with TBG-1/gamma-tubulin to centrosomes during interphase and mitosis; GIP-1 and TBG-1 are required reciprocally for centrosomal localization.
Molecular_info (6)
Experimental_info RNAi_result (6)
WB_RNAi_result (9)
Y2H_bait (49)
Reference WBPaper00005320
WBPaper00005041
RemarkSequence connection from [Hannak E], 02/06/11 krb.
MethodGene