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Gene: H06O01.1   

Identity (5)
Gene_info Gene_classpdi
GO_term GO:0016853 IEA Inferred_automatically
GO:0005783 IEA Inferred_automatically
GO:0005489 IEA Inferred_automatically
GO:0006118 IEA Inferred_automatically
Structured_description Provisional_description (12)
Concise_descriptionpdi-3 encodes a protein disulfide isomerase (PDI) required for normal cuticle collagen deposition and, subliminally, for maintenance of normal body shape; PDI-3 has both PDI and calcium-dependent transglutaminase activity in vitro, crosslinking proteins through a gamma-glutamyl epsilon-lysine dual residue; PDI-3 is homologous to the human PDI ERp60, as well as a homolog in the dog heartworm Dirofilaria immitis that is required for larval molting; the joint PDI/transglutaminase activity of PDI-3 is biochemically conserved in nematodes and mammals; pdi-3 is constitutively and broadly expressed, particularly in gut and hypodermis.
Molecular_info (5)
Experimental_info RNAi_result (5)
WB_RNAi_result (6)
Expr_pattern (5)
Y2H_target Y2H005923
Reference (4)