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Gene: K03H1.2   

K03H1.2SMapS_parentSequenceK03H1
ChromosomeIII
Identity (5)
Gene_info Gene_classmog
Allele q151
q223 Inferred_automaticallyFrom strain object: JK1389
q376
q473
Phenotype[C.elegansII] q223 : hermaphrodite germline makes 300-500 sperm, no oocytes; no somatic defects; males WT. q223/Df similar. OA5: q151, q161, q370, q471 (all similar),q473 (viable, some oogenesis, more at 15C). mog-1; fem-1 or mog-1; fem-3 double mutant hermaphrodites make oocytes, but are Mel (variable embryonic arrest). [Graham and Kimble 1993]
StrainJK1389
GO_term GO:0005524 IEA Inferred_automatically
GO:0008026 IEA Inferred_automatically
GO:0003676 IEA Inferred_automatically
GO:0004386 IEA Inferred_automatically
Contained_in_operonCEOP3642
Structured_description Provisional_description The mog-1 gene encodes a DEAH helicase orthologous to the Drosophila CG1375/1405, the human PRP16, and the S. cerevisiae PRP16 proteins.Paper_evidenceWBPaper00004587
Person_evidenceWBPerson567
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Such helicases, in Drosophila, are part of a complex of proteins (including DEAH helicass and MYST acetyltransferases) and RNAs called the 'compensasome' that mediates dosage compensation.
The components of the compensasome are generally conserved in metazoa: they thus are likely to act as a functional unit in C. elegans and other metazoa, and not merely in Drosophila alone.
Concise_descriptionThe mog-1 gene encodes a DEAH helicase orthologous to the Drosophila CG1375/1405, the human PRP16, and the S. cerevisiae PRP16 proteins.
Molecular_info (6)
Experimental_info RNAi_result (6)
WB_RNAi_result (6)
Expr_pattern Expr1267
Expr1268
Interaction WBInteraction0000151
WBInteraction0000153
WBInteraction0003216
Reference (36)
MethodGene