R05F9.8 | SMap | S_parent | Sequence | R05F9
|
| Chromosome | II |
|
Identity
| Version | 1 |
| |
Name
| CGC_name | msp-33
| Person_evidence | WBPerson680
|
| | | Sequence_name | R05F9.8
|
| | |
Molecular_name
| R05F9.8
|
| | | | WP:CE04811
|
| | | | CE04811
|
| | | Other_name |
NM_062487
| Inferred_automatically |
| | | | | Date_last_updated | 15 Apr 2005 00:00:00 |
WS142
|
| | | | | | |
| | | Public_name | msp-33
|
| | |
Synonym (5)
|
| | | WBGeneID | WBGene00003431
|
| | Species | Caenorhabditis elegans
|
| | History | Version_change | 1 | 07 Apr 2004 11:29:31 | WBPerson1971
| Event | Imported | Initial conversion from geneace |
| | Status | Live |
|
Gene_info
| Gene_class | msp
|
| | Phenotype | [C.elegansII] NMK. Encodes MSP (16kD); msp-152 cluster. [Ward et al. (1988); BA] |
| | GO_term | GO:0005198
| IEA
| Inferred_automatically |
| |
Structured_description
| Provisional_description | msp-33 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-33 has a C. briggsae homolog as predicted by the Wobble Aware Bulk Aligner (WABA); the MSP family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Paper_evidence (5)
|
| | | | | Curator_confirmed | WBPerson324
|
| | | | | Date_last_updated | 06 May 2005 00:00:00 |
| | | Concise_description | msp-33 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-33 has a C. briggsae homolog as predicted by the Wobble Aware Bulk Aligner (WABA); the MSP family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
|
Molecular_info
| Corresponding_CDS | R05F9.8
|
| | Corresponding_protein | WP:CE04811
|
| |
Corresponding_PCR_product (54)
|
| |
Corresponding_RNAi_reagent (56)
|
|
Experimental_info
|
RNAi_result
| Cenix:211-g4
|
| | | JA:R05F9.8
|
| | | [cgc5655]:R05F9.8
|
| | | [cgc5655]:daf-2:R05F9.8
|
| | | [cgc5655]:tph-1:R05F9.8
|
| | | [cgc5655]:tub-1:R05F9.8
|
| |
WB_RNAi_result (72)
|
| | Expr_pattern | Expr3417
|
|
Reference
| WBPaper00001023
|
| | WBPaper00015440
|
| | WBPaper00025088
|
| Method | Gene
|