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Gene: T11G6.1   

T11G6.1SMapS_parentSequenceT11G6
ChromosomeIV
Identity (5)
Gene_info Gene_classhrs
GO_term (7)
Contained_in_operonCEOP4396
Structured_description Provisional_description hrs-1 encodes predicted cytoplasmic and mitochondrial histidyl-tRNA synthetases (HisRS), class II aminoacyl-tRNA synthetases that catalyze the attachment of histidine to its cognate tRNAs and are thus required for protein biosynthesis; HRS-1 synthetases are required for embryogenesis, germline development, wild type body morphology, and normal rates of postembryonic growth. Paper_evidence WBPaper00004424
WBPaper00005654
Person_evidenceWBPerson1843
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
This gene encodes a protein predicted by Eisenberg and coworkers, with 52% accuracy, to be mitochondrial.
Concise_descriptionhrs-1 encodes predicted cytoplasmic and mitochondrial histidyl-tRNA synthetases (HisRS), class II aminoacyl-tRNA synthetases that catalyze the attachment of histidine to its cognate tRNAs and are thus required for protein biosynthesis; HRS-1 synthetases are required for embryogenesis, germline development, wild type body morphology, and normal rates of postembryonic growth.
Molecular_info (5)
Experimental_info RNAi_result Cenix:54-e2
JA:T11G6.1
Simmer:T11G6.1
WB_RNAi_result JA:T11G6.1
Simmer:T11G6.1
MV_SV:mv_AAB38116
Cenix:54-e2
Y2H_targetY2H005979
Remark 2230 nt gene encoding 525 aa predicted protein with extensive similarity to yeast and human histidyl-tRNA synthetases
Data extracted from Amaar and Baillie, 1993
1a is cytoplasmic and 1b is mitochondrial based on PSORT, iPSORT and SignalP analysis [030411 ck1]Curator_confirmedWBPerson1846
MethodGene