Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
 

Gene: Y104H12A.1   

Y104H12A.1SMapS_parentSequenceSUPERLINK_RW4
ChromosomeIV
Identity (5)
Gene_info Gene_classnhr
Allele ok584 Inferred_automaticallyFrom strain object: RB794
cxP5010
snp_Y77E11[1]
StrainRB794
Structured_description Provisional_descriptionnhr-41 encodes a nuclear receptor of the NR2D1 subfamily that is orthologous to the Drosophila DHR78 nuclear receptor essential for the onset of metamorphosis, and the mammalian TR2 and TR4 receptors which are expressed in androgen-sensitive organs and brain tissue, respectively; by homology, NHR-41 likely functions as a transcription factor that, based upon RNAi experiments, plays a role in the formation of SDS-resistant dauer larvae; using two different reporter fusions, nhr-41 expression is detected in seam cells, excretory cells, and rectal epithelia, or in chemosensory neurons, gut, and head and tail hypodermis; nhr-41 mRNAs are expressed at all larval stages at precise intervals relative to molting: mRNA produced by upstream promoter sequence is detected at the time larval molts occur, while mRNA produced by promoter sequence in the fourth intron is detected at variable levels during larval development with distinct peaks of expression seen at the beginning of the intermolt.Paper_evidenceWBPaper00006412
Curator_confirmedWBPerson1843
Date_last_updated07 Feb 2005 00:00:00
Concise_descriptionnhr-41 encodes a nuclear receptor of the NR2D1 subfamily that is orthologous to the Drosophila DHR78 nuclear receptor essential for the onset of metamorphosis, and the mammalian TR2 and TR4 receptors which are expressed in androgen-sensitive organs and brain tissue, respectively; by homology, NHR-41 likely functions as a transcription factor that, based upon RNAi experiments, plays a role in the formation of SDS-resistant dauer larvae; using two different reporter fusions, nhr-41 expression is detected in seam cells, excretory cells, and rectal epithelia, or in chemosensory neurons, gut, and head and tail hypodermis; nhr-41 mRNAs are expressed at all larval stages at precise intervals relative to molting: mRNA produced by upstream promoter sequence is detected at the time larval molts occur, while mRNA produced by promoter sequence in the fourth intron is detected at variable levels during larval development with distinct peaks of expression seen at the beginning of the intermolt.
Molecular_info (5)
Experimental_info RNAi_result Cenix:134-d9
Cenix:191-b8
JA:Y104H12A.1
JA:Y77E11A_3443.a
WB_RNAi_result (5)
Expr_pattern Expr2869
Expr2870
Expr2871
Y2H_target (11)
Reference (5)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene