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Gene: Y47G6A.20   

Y47G6A.20Evidence Person_evidence WBPerson71
WBPerson395
SMapS_parentSequenceY47G6A
ChromosomeI
Identity (5)
Gene_info Gene_classrnp
GO_term GO:0000166 IEA Inferred_automatically
GO:0003676 IEA Inferred_automatically
Structured_description Provisional_description rnp-6 encodes an ortholog of HALF-PINT in D. melanogaster and FBP Interacting Repressor (FIR)/PUF60 in mammals, predicted to be involved in mRNA splicing regulation, mRNA localization, or transcriptional regulation via TFIIH. Paper_evidence WBPaper00012787
WBPaper00012860
WBPaper00013021
Person_evidenceWBPerson567
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
HALF-PINT regulates RNA splicing, is required for normal RNA localization during oogenesis, functions in both constitutive and alternative splicing in vivo, and is specifically required in vivo for a developmentally regulated splice form of the ovarian tumor gene.
FBP Interacting Repressor (FIR)/PUF60 blocks the transcriptional activation of c-myc by FUSE binding protein, via TFIIH subunits p62, p89, and Cyclin H, and, at the same time, enables the binding of U2 snRNP to pre-mRNA in conjunction with the large subunit of U2AF, U2AF65.
Concise_descriptionrnp-6 encodes an ortholog of HALF-PINT in D. melanogaster and FBP Interacting Repressor (FIR)/PUF60 in mammals, predicted to be involved in mRNA splicing regulation, mRNA localization, or transcriptional regulation via TFIIH.
Molecular_info Corresponding_CDS Y47G6A.20a
Y47G6A.20b
Y47G6A.20c
Corresponding_protein WP:CE24365
WP:CE24366
WP:CE31375
Corresponding_PCR_product sjj_Y47G6A_245.f
sjj_Y47G6A_245.g
Corresponding_RNAi_reagent Cenix:90-g11
sjj_Y47G6A_245.f
sjj_Y47G6A_245.g
mv_Y47G6A.20a
Experimental_info RNAi_result (6)
WB_RNAi_result (7)
MethodGene