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Gene: Y54E5B.3   

Y54E5B.3SMapS_parentSequenceY54E5B
ChromosomeI
Identity (5)
Gene_info Gene_classlet
Reference_allelest44
Allelest44 Inferred_automaticallyFrom strain object: RW3199
Phenotype st44 : mid-larval lethal. NA1.
[C.elegansII] st44 : mid-larval lethal. NA1. [Anderson and Brenner 1984; RW]
StrainRW3199
GO_term GO:0003713 IEA Inferred_automatically
GO:0045941 IEA Inferred_automatically
GO:0005634 IEA Inferred_automatically
Contained_in_operonCEOP1768
Structured_description Provisional_descriptionlet-49 encodes a putative mediator complex subunit zygotically required for postembryonic development and viability past larval stages, while being maternally required for germline and embryonic development; LET-49 is an ortholog of human CRSP9 (OMIM:605045) and of S. cerevisiae Med7p; Med7p is a component of a mediator complex that serves as a transcriptional coactivator, while CRSP9 mediates transcriptional activation by Sp1. Paper_evidence (5)
Person_evidenceWBPerson567
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Concise_descriptionlet-49 encodes a putative mediator complex subunit zygotically required for postembryonic development and viability past larval stages, while being maternally required for germline and embryonic development; LET-49 is an ortholog of human CRSP9 (OMIM:605045) and of S. cerevisiae Med7p; Med7p is a component of a mediator complex that serves as a transcriptional coactivator, while CRSP9 mediates transcriptional activation by Sp1.
Molecular_info (5)
Experimental_info RNAi_result JA:Y54E5B.3
Simmer:Y54E5B.3:Screen_A
Simmer:Y54E5B.3:Screen_B
Cenix:34-c8
WB_RNAi_result (5)
Reference (8)
MethodGene