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Gene: ZK546.6   

ZK546.6SMapS_parentSequenceZK546
ChromosomeII
Identity (5)
Gene_info Gene_classmsp
Phenotype Cluster of five genes including msp-152 (transcribed).
[C.elegansII] NMK. Encodes MSP (16kD). Defines cluster of five genes including msp-152 (transcribed). [Ward et al. (1988); BA]
GO_termGO:0005198 IEA Inferred_automatically
Structured_description Provisional_descriptionmsp-152 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. Paper_evidence (5)
Curator_confirmedWBPerson324
Date_last_updated17 May 2005 00:00:00
Concise_descriptionmsp-152 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.
Molecular_info Corresponding_CDSZK546.6
Corresponding_proteinWP:CE02920
Corresponding_PCR_product smd_C34F11.4
smd_F32B6.6
smd_F36H12.7
smd_F36H12.7:2
smd_F36H12.8
smd_F58A6.9
smd_K07F5.2
smd_R05F9.3
smd_R13H9.4
smd_T13F2.10
smd_Y59E9_120.c
smd_ZK354.1
smd_ZK354.11
smd_ZK546.3
smd_ZK546.6
smd_ZK1251.6
sjj_ZK546.6
sjj_R13H9.4
sjj_Y59E9_120.c
sjj_ZK354.1
sjj_R05F9.13
sjj_F26G1.7
sjj_R05F9.8
sjj_T13F2.10
sjj_K07F5.2
sjj_ZK1251.6
sjj_R05F9.5
sjj_ZK354.11
sjj_F09C12.7
sjj_C34F11.4
sjj_F32B6.6
sjj_Y59E9_120.c_1
sjj_R05F9.3
sjj_ZK546.3
sjj_F58A6.8
sjj_F36H12.7
sjj_Y59E9_120.c_2
Corresponding_RNAi_reagent (40)
Experimental_info RNAi_result JA:ZK546.6
Simmer:ZK546.6:Repeat_a
Simmer:ZK546.6:Repeat_b
Simmer:ZK546.6:Screen
WB_RNAi_result (69)
Expr_patternExpr3417
Reference WBPaper00001023
WBPaper00001024
WBPaper00024312
WBPaper00025088
MethodGene