| Ace View of Cenix:122-a4 | |||||||||
| Gene Inhibited | T20F5.2 (pbs-4) | ||||||||
| Description of "T20F5.2" | pbs-4 encodes a B-type subunit of the 26S proteasome's 20S protease core particle; by homology, PBS-4 is predicted to function in ATP/ubiquitin-dependent nonlysosomal protein degradation; loss of pbs-4 activity via RNAi indicates that, in C. elegans, PBS-4 is required for embryonic, germline, and larval development. | ||||||||
| KOG Annotation | 20S proteasome, regulatory subunit beta type PSMB2/PRE1 |
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| Evidence for Inhibition |
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| External "T20F5.2" Links |    1 |
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| Embryonic | Emb Penetrance None reported | ||||||||
| Phenotype | Passage Through Meiosis defective |
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| External Movies (Please note that RNAiDB is not hosting these data.) |
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| Laboratory | TH | ||||||||
| RNAi Reagent & Type | Cenix:122-a4 (PCR_reagent) | ||||||||
| Remark | early embryonic: Passage Through Meiosis | ||||||||
| Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||||||||
| Delivery Method | Injection | ||||||||
| Date | 2005-3-24 | ||||||||
| Gene Plot of T20F5.2 | |||||||||
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