Advanced Phenotype Search (Combinatorial Query Builder):

Phenotype = contains exists does not exist begins with ends with != > >= < <= COUNT = COUNT != COUNT > COUNT >= COUNT < COUNT <= AB aster resembles P1 aster AB nuclear migration abnormal AB or P1 spindle orientation aberrant AB spindle orientation abnormal ABa, ABp and EMS divide synchronously Aberrant AB or P1 spindle orientation Aberrant cell-cell contacts at the four-cell stage Aberrant Cytoplasmic Structures Aberrant nuclear reassembly Abnormal blebbing Abnormal coloration Abnormal one-cell shape Abnormal pronuclei Abnormal size of pronucleus Abs Adl Age aldicarb_resistant Altered cell-cell contacts Altered timing of second division Altered timing of second division (synchrony) Areas devoid of yolk granules Asymmetry of Division abnormal Bli Bmd Catastrophic one-cell arrest Ced Centrosome Attachment abnormal Chromosome Segregation (karyomeres) abnormal Clr Complex Phenotype Con Cortical Dynamics abnormal Cpa Cyk Cytokinesis defect Cytokinesis problems Daf Defect Delayed at pronuclear contact Delayed P0 spindle rotation Delayed P1 division Developmental Delay Division axis of ABa or ABp aberrant Dpy Dramatic cytoplasmic blebbing Ectopic cleavage furrows Ectopic furrows Egg production ceases in injected animal Egg shape/size abnormal Egg Size abnormal Egl Emb embryonic defect Embryos arrest at different stages EMS divides after and is smaller than P2 EMS divides before and is smaller than P1 EMS extends too far anteriorly EMS fails to extend anteriorly Entry Into Interphase abnormal Esp Etv Evl Exaggerated asynchrony Exaggerated pseudocleavage Excessive blebbing Failure to form pronucleus Fem Fgc Fog Four-cell stage configuration abnormal Four-cell stage nuclei: size/shape abnormal Four-cell stage: cross-eyed General Pace of Development abnormal Glp Gom Gon Granular cytoplasm Gro Growth defect Him Hya Inadequate test Indistinct maternal pronucleus Integrity of Membranous Organelles defective Lag Large cytoplasmic granules Larval Arrest-Early (L1/L2) Larval Arrest-Late (L3/L4) Larval Lethal-Early (L1/L2) Larval Lethal-Late (L3/L4) Led Let Lethal Lin Lon Loose mitotic furrow Loose spindle Lpd Lva Lvl Mab Mec Mei Meiotic arrest Mel Mig Mlt Mog Morphology defect Movement defect Mul mult Multiple cavities Multiple maternal pronuclei Multiple nuclei Multiple nuclei in 1, 2, or 4-cell embryos Multiple paternal pronuclei or aberrant centrosomes Multiple vacuoles Mut Muv Nmo No developing embryos seen 48 hours after dsRNA injection no escapers Npo Nuclear Appearance abnormal Nuclei reform next to cell division remnant Number/age of embryos atypical Ocs Oma Ooc Osmotic Integrity defective Osmotic sensitivity Osmotically/ pressure sensitive Oth Other Overall pace of events slow P0 cortical ruffling abnormal P0 cytokinesis: completion/stability abnormal P0 cytokinesis: furrow ingression abnormal P0 cytokinesis: furrow specification abnormal P0 cytoplasmic flows reduced/absent P0 pronuclear centration absent P0 pronuclear envelope breakdown delayed P0 pronuclear meeting position abnormal P0 pronuclear migration reduced/absent (female) P0 pronuclear migration reduced/absent (male) P0 pronuclear rotation P0 pronuclei: number abnormal P0 pronuclei: size/shape abnormal P0 pseudo-cleavage furrow abnormal P0 spindle absent P0 spindle assembly: bipolarity abnormal P0 spindle does not rotate P0 spindle elongation abnormal P0 spindle integrity abnormal P0 spindle poles abnormal P0 spindle positioning defect P0 spindle positioning problems P0 spindle positioning problems (posterior) P0 spindle positioning: asymmetry abnormal P0 spindle rocking abnormal P1 aster abnormal P1 nuclear migration/rotation absent/reduced P1/AB asynchrony of divisions abnormal P1/AB cortical activity exaggerated P1/AB cytokinesis abnormal P1/AB nuclear separation: cross-eyed P1/AB nuclei: number abnormal P1/AB nuclei: size/shape abnormal P1/AB spindle assembly abnormal P2 and EMS divide synchronously Pace of P-Lineage abnormal Passage Through Meiosis defective Pat Patchy Paternal pronucleus migrates Pch Pleiotropic Pna Pnm Polar bodies abnormal Polar body reabsorbed post-embryonic defect Prl Prm Pro Pronuclear breakdown asynchronous Pronuclear migration defects Pronuclear/Nuclear Appearance abnormal Pronuclei can meet centrally Pronuclei fail to migrate Pronuclei meet more centrally Prz Pseudocleavage absent Pseudocleavage problems Pvl Pvu Rde Reduced fecundity of injected worm Reproductive defect Reversed asynchrony Rol Rot Rup Sck Severe Pleiotropic Defects Sister Chromatid Separation abnormal (Cross-eyed) Sle Slow cell cycle Slu Sma Small embryos Spd Spi Spindle Assembly abnormal Spindle Elongation/Integrity abnormal Spindle positioning problems Spn Spo Ste Sterile F0/Fertility Problems Sterile F1 Sterility/Impaired Fertility in F0 Stp Stress Resistance Synchronous second division Tetrapolar spindle Tum Unc Unclassified Unclear: multinucleate Unfertilized oocytes laid Var Vul WT WT_postembryonic_morphology Yolk granules: density reduced Yolk granules: size abnormal END AND OR XOR AND NOT OR NOT XOR NOT
Phenotype = contains exists does not exist begins with ends with != > >= < <= COUNT = COUNT != COUNT > COUNT >= COUNT < COUNT <= AB aster resembles P1 aster AB nuclear migration abnormal AB or P1 spindle orientation aberrant AB spindle orientation abnormal ABa, ABp and EMS divide synchronously Aberrant AB or P1 spindle orientation Aberrant cell-cell contacts at the four-cell stage Aberrant Cytoplasmic Structures Aberrant nuclear reassembly Abnormal blebbing Abnormal coloration Abnormal one-cell shape Abnormal pronuclei Abnormal size of pronucleus Abs Adl Age aldicarb_resistant Altered cell-cell contacts Altered timing of second division Altered timing of second division (synchrony) Areas devoid of yolk granules Asymmetry of Division abnormal Bli Bmd Catastrophic one-cell arrest Ced Centrosome Attachment abnormal Chromosome Segregation (karyomeres) abnormal Clr Complex Phenotype Con Cortical Dynamics abnormal Cpa Cyk Cytokinesis defect Cytokinesis problems Daf Defect Delayed at pronuclear contact Delayed P0 spindle rotation Delayed P1 division Developmental Delay Division axis of ABa or ABp aberrant Dpy Dramatic cytoplasmic blebbing Ectopic cleavage furrows Ectopic furrows Egg production ceases in injected animal Egg shape/size abnormal Egg Size abnormal Egl Emb embryonic defect Embryos arrest at different stages EMS divides after and is smaller than P2 EMS divides before and is smaller than P1 EMS extends too far anteriorly EMS fails to extend anteriorly Entry Into Interphase abnormal Esp Etv Evl Exaggerated asynchrony Exaggerated pseudocleavage Excessive blebbing Failure to form pronucleus Fem Fgc Fog Four-cell stage configuration abnormal Four-cell stage nuclei: size/shape abnormal Four-cell stage: cross-eyed General Pace of Development abnormal Glp Gom Gon Granular cytoplasm Gro Growth defect Him Hya Inadequate test Indistinct maternal pronucleus Integrity of Membranous Organelles defective Lag Large cytoplasmic granules Larval Arrest-Early (L1/L2) Larval Arrest-Late (L3/L4) Larval Lethal-Early (L1/L2) Larval Lethal-Late (L3/L4) Led Let Lethal Lin Lon Loose mitotic furrow Loose spindle Lpd Lva Lvl Mab Mec Mei Meiotic arrest Mel Mig Mlt Mog Morphology defect Movement defect Mul mult Multiple cavities Multiple maternal pronuclei Multiple nuclei Multiple nuclei in 1, 2, or 4-cell embryos Multiple paternal pronuclei or aberrant centrosomes Multiple vacuoles Mut Muv Nmo No developing embryos seen 48 hours after dsRNA injection no escapers Npo Nuclear Appearance abnormal Nuclei reform next to cell division remnant Number/age of embryos atypical Ocs Oma Ooc Osmotic Integrity defective Osmotic sensitivity Osmotically/ pressure sensitive Oth Other Overall pace of events slow P0 cortical ruffling abnormal P0 cytokinesis: completion/stability abnormal P0 cytokinesis: furrow ingression abnormal P0 cytokinesis: furrow specification abnormal P0 cytoplasmic flows reduced/absent P0 pronuclear centration absent P0 pronuclear envelope breakdown delayed P0 pronuclear meeting position abnormal P0 pronuclear migration reduced/absent (female) P0 pronuclear migration reduced/absent (male) P0 pronuclear rotation P0 pronuclei: number abnormal P0 pronuclei: size/shape abnormal P0 pseudo-cleavage furrow abnormal P0 spindle absent P0 spindle assembly: bipolarity abnormal P0 spindle does not rotate P0 spindle elongation abnormal P0 spindle integrity abnormal P0 spindle poles abnormal P0 spindle positioning defect P0 spindle positioning problems P0 spindle positioning problems (posterior) P0 spindle positioning: asymmetry abnormal P0 spindle rocking abnormal P1 aster abnormal P1 nuclear migration/rotation absent/reduced P1/AB asynchrony of divisions abnormal P1/AB cortical activity exaggerated P1/AB cytokinesis abnormal P1/AB nuclear separation: cross-eyed P1/AB nuclei: number abnormal P1/AB nuclei: size/shape abnormal P1/AB spindle assembly abnormal P2 and EMS divide synchronously Pace of P-Lineage abnormal Passage Through Meiosis defective Pat Patchy Paternal pronucleus migrates Pch Pleiotropic Pna Pnm Polar bodies abnormal Polar body reabsorbed post-embryonic defect Prl Prm Pro Pronuclear breakdown asynchronous Pronuclear migration defects Pronuclear/Nuclear Appearance abnormal Pronuclei can meet centrally Pronuclei fail to migrate Pronuclei meet more centrally Prz Pseudocleavage absent Pseudocleavage problems Pvl Pvu Rde Reduced fecundity of injected worm Reproductive defect Reversed asynchrony Rol Rot Rup Sck Severe Pleiotropic Defects Sister Chromatid Separation abnormal (Cross-eyed) Sle Slow cell cycle Slu Sma Small embryos Spd Spi Spindle Assembly abnormal Spindle Elongation/Integrity abnormal Spindle positioning problems Spn Spo Ste Sterile F0/Fertility Problems Sterile F1 Sterility/Impaired Fertility in F0 Stp Stress Resistance Synchronous second division Tetrapolar spindle Tum Unc Unclassified Unclear: multinucleate Unfertilized oocytes laid Var Vul WT WT_postembryonic_morphology Yolk granules: density reduced Yolk granules: size abnormal END AND OR XOR AND NOT OR NOT XOR NOT

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